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Cellosaurus HeLa S3 RUBCN KO clone 15 (CVCL_D5AG)

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Cell line name HeLa S3 RUBCN KO clone 15
Synonyms Rubicon KO HeLa
Accession CVCL_D5AG
Resource Identification Initiative To cite this cell line use: HeLa S3 RUBCN KO clone 15 (RRID:CVCL_D5AG)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28991; RUBCN.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0058 (HeLa S3)
Children:
CVCL_D5AJ (HeLa S3 RUBCN KO/HA-Parkin/HaloTag7-mGFP)CVCL_D5AK (HeLa S3 RUBCN KO/HaloTag7-LC3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=38728007; DOI=10.1083/jcb.202309015; PMCID=PMC11090050
Tudorica D.A., Basak B., Puerta Cordova A.S., Khuu G., Rose K.M., Lazarou M., Holzbaur E.L.F., Hurley J.H.
A RAB7A phosphoswitch coordinates Rubicon homology protein regulation of parkin-dependent mitophagy.
J. Cell Biol. 223:e202309015.1-e202309015.18(2024)

Cross-references
Encyclopedic resources Wikidata; Q127381693
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number4