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Cellosaurus JMRD3 (CVCL_D592)

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Cell line name JMRD3
Accession CVCL_D592
Resource Identification Initiative To cite this cell line use: JMRD3 (RRID:CVCL_D592)
Comments Selected for resistance to: ChEBI; CHEBI_73558; Vitamin D3.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D591 (RWLeu-4)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7994044; DOI=10.1182/blood.V84.12.4283.bloodjournal84124283
Stephen R. Lasky, Marshall R. Posner, Keigo Iwata, Anabel Santos-Moore, Andrew Yen, Varman Samuel, Jeffrey William Clark, Abby Lee Maizel;
Characterization of a vitamin D3-resistant human chronic myelogenous leukemia cell line.
Blood 84:4283-4294(1994)

PubMed=8635507; DOI=10.1006/excr.1996.0165
Keigo Iwata, Nicola Kouttab, Haruki Ogata, John W. Morgan, Abby Lee Maizel, Stephen R. Lasky;
Differential regulation of vitamin D receptors in clonal populations of a chronic myelogenous leukemia cell line.
Exp. Cell Res. 225:143-150(1996)

Cross-references
Encyclopedic resources Wikidata; Q54899010
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number12