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Cellosaurus HER14 (CVCL_D576)

[Text version]
Cell line name HER14
Synonyms NIH3T3-Her14; DHER14; HER 14
Accession CVCL_D576
Resource Identification Initiative To cite this cell line use: HER14 (RRID:CVCL_D576)
Comments Characteristics: Expresses ~200000 EGFR (PubMed=1417788).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3236; EGFR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=3501826; DOI=10.1128/mcb.7.12.4568-4571.1987; PMCID=PMC368145
Honegger A., Szapary D., Schmidt A., Lyall R.M., Van Obberghen E., Dull T.J., Ullrich A., Schlessinger J.
A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis.
Mol. Cell. Biol. 7:4568-4571(1987)

PubMed=1417788; DOI=10.1042/bj2870037; PMCID=PMC1133120
Spaargaren M., Wissink S., Defize L.H.K., de Laat S.W., Boonstra J.
Characterization and identification of an epidermal-growth-factor-activated phospholipase A2.
Biochem. J. 287:37-43(1992)

Cross-references
Anatomy/cell type resources BTO; BTO_0005263
Encyclopedic resources Wikidata; Q54882890
Experimental variables resources EFO; EFO_0022731
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16