Cellosaurus DLD-1 PIK3CA (E545K/-) (CVCL_D4XI)
| Cell line name | DLD-1 PIK3CA (E545K/-) |
|---|---|
| Synonyms | PIK3CA^(E545K/-) DLD-1 |
| Accession | CVCL_D4XI |
| Resource Identification Initiative | To cite this cell line use: DLD-1 PIK3CA (E545K/-) (RRID:CVCL_D4XI) |
| Comments | Population: Caucasian. Characteristics: In DLD-1 one of the two PIK3CA alleles has a p.Glu545Lys mutation. This cell line is KO for the wild-type allele (PubMed=15950905). Knockout cell: Method=Recombinant Adeno-Associated Virus; HGNC; HGNC:8975; PIK3CA (Note=1 of 2 alleles). Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Disease | Colon adenocarcinoma (NCIt: C4349) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0248 (DLD-1) |
| Sex of cell | Male |
| Age at sampling | 67Y |
| Category | Cancer cell line |
| Publications | PubMed=15950905; DOI=10.1016/j.ccr.2005.05.014 |
| Cross-references | |
| Cell line collections (Providers) | Horizon_Discovery; HD+105-012 |
| Encyclopedic resources | Wikidata; Q127380795 |
| Entry history | |
| Entry creation | 02-May-2024 |
| Last entry update | 10-Apr-2025 |
| Version number | 4 |