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Cellosaurus Don QR (CVCL_D3W6)

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Cell line name Don QR
Synonyms CdtRQ-Rev
Accession CVCL_D3W6
Resource Identification Initiative To cite this cell line use: Don QR (RRID:CVCL_D3W6)
Comments Characteristics: Revertant, lost the resistance to the Rho-modifying glucosyltransferase toxins A and B of Clostridium difficile (PubMed=9295324).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; UniProtKB; O35156; Ugp2; Simple; p.Gly116Asp; Zygosity=Heterozygous (PubMed=9295324).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_J503 (Don Q)
Sex of cell Male
Age at sampling 8M
Category Spontaneously immortalized cell line
Publications

PubMed=9295324; DOI=10.1074/jbc.272.38.23784
Marietta Flores-Diaz, Alberto Alape-Giron, Bengt Persson, Piero Pollesello, Michael Moos, Christoph von Eichel-Streiber, Monica Thelestam, Inger Florin;
Cellular UDP-glucose deficiency caused by a single point mutation in the UDP-glucose pyrophosphorylase gene.
J. Biol. Chem. 272:23784-23791(1997)

Cross-references
Encyclopedic resources Wikidata; Q127380799
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3