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Cellosaurus HAP1 RAB10 (-) 2 (CVCL_D3U7)

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Cell line name HAP1 RAB10 (-) 2
Synonyms HZGHC008098c007; RAB10 knockout cell line 28bp deletion
Accession CVCL_D3U7
Resource Identification Initiative To cite this cell line use: HAP1 RAB10 (-) 2 (RRID:CVCL_D3U7)
Comments Group: Haploid karyotype cell line.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9759; RAB10.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y019 (HAP1)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

DOI=10.12688/f1000research.156209.1
Vera Ruiz Moleon, Charles Alende, Maryam Fotouhi, Kathleen Southern, Riham Ayoubi, Carl Laflamme;
ABIF Consortium
NeuroSGC/YCharOS/EDDU Collaborative Group
A guide to selecting high-performing antibodies for Rab10 (UniProt ID: P61026) for use in western blot, immunoprecipitation, and immunofluorescence.
F1000Research 13:1061.1-1061.13(2024)

Cross-references
Cell line collections (Providers) Horizon_Discovery; HZGHC008098c007
Encyclopedic resources Wikidata; Q127381084
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number5