ID   HAP1 RAB10 (-) 2
AC   CVCL_D3U7
SY   HZGHC008098c007; RAB10 knockout cell line 28bp deletion
DR   Horizon_Discovery; HZGHC008098c007
DR   Wikidata; Q127381084
RX   DOI=10.12688/f1000research.156209.1;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9759; RAB10.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 5
//
RX   DOI=10.12688/f1000research.156209.1;
RA   Ruiz Moleon V., Alende C., Fotouhi M., Southern K., Ayoubi R.,
RA   Laflamme C.;
RG   ABIF Consortium;
RG   NeuroSGC/YCharOS/EDDU Collaborative Group;
RT   "A guide to selecting high-performing antibodies for Rab10 (UniProt
RT   ID: P61026) for use in western blot, immunoprecipitation, and
RT   immunofluorescence.";
RL   F1000Research 13:1061.1-1061.13(2024).
//