Cellosaurus logo
expasy logo

Cellosaurus KM641 (CVCL_D3P7)

[Text][XML][JSON]
Cell line name KM641
Synonyms KM-641
Accession CVCL_D3P7
Resource Identification Initiative To cite this cell line use: KM641 (RRID:CVCL_D3P7)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-3116.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the chimeric (mouse/human) ecromeximab (KM871) therapeutic antibody developed for the treatment of malignant melanoma.
Monoclonal antibody isotype: IgG3, kappa.
Monoclonal antibody target: ChEBI; CHEBI_89636; Ganglioside GD3.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3412 (P3X63Ag8U.1)
Category Hybridoma
Publications

Patent=EP0493686B1
Nobuo Hanai, So Ohta;
Monoclonal antibodies to glycolipid carbohydrate chains.
Patent number EP0493686B1, 12-Feb-1991

PubMed=8439988; DOI=10.1007/BF01740908; PMCID=PMC11038899
So Ohta, Ayumi Honda, Yuko Tokutake, Hajime Yoshida, Nobuo Hanai;
Antitumor effects of a novel monoclonal antibody with high binding affinity to ganglioside GD3.
Cancer Immunol. Immunother. 36:260-266(1993)

Cross-references
Encyclopedic resources Wikidata; Q127382552
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3