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Cellosaurus KM1259 (CVCL_D3P4)

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Cell line name KM1259
Accession CVCL_D3P4
Resource Identification Initiative To cite this cell line use: KM1259 (RRID:CVCL_D3P4)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-5134.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized benralizumab (MEDI-563; Fasenra) therapeutic antibody used for the treatment of severe eosinophilic asthma.
Monoclonal antibody isotype: IgG1.
Monoclonal antibody target: UniProtKB; Q01344; Human IL5RA/CD125.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3412 (P3X63Ag8U.1)
Category Hybridoma
Publications

Patent=US7238354
Masamichi Koike, Akiko Furuya, Kazuyasu Nakamura, Akihoro Iida, Hideharu Anazawa, Nobuo Hanai, Kiyoshi Takatsu;
Method of treating atopic dermatitis using antibody against human interleukin-5 receptor alpha chain.
Patent number US7238354, 03-Jul-2007

PubMed=19478395; DOI=10.3233/HAB-2009-0198
Masamichi Koike, Kazuyasu Nakamura, Akiko Furuya, Akihoro Iida, Hideharu Anazawa, Kiyoshi Takatsu, Nobuo Hanai;
Establishment of humanized anti-interleukin-5 receptor alpha chain monoclonal antibodies having a potent neutralizing activity.
Hum. Antibodies 18:17-27(2009)

Cross-references
Encyclopedic resources Wikidata; Q127382439
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2