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Cellosaurus iBMK W2 (CVCL_D3G2)

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Cell line name iBMK W2
Synonyms W2; immortalized Baby Mouse Kidney epithelial cell line W2
Accession CVCL_D3G2
Resource Identification Initiative To cite this cell line use: iBMK W2 (RRID:CVCL_D3G2)
Comments Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax (Note=1 of 2 alleles).
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_D3GS (iBMK W2.3.1-2)CVCL_D3GT (iBMK W2.3.1-5)CVCL_D3GU (iBMK W2.3.1-6)
CVCL_D3GV (iBMK W2.A1)CVCL_D3GY (iBMK W2.Akt-C1)CVCL_D3GZ (iBMK W2.Akt-D1)
CVCL_D3H0 (iBMK W2.Akt-E4)CVCL_D3GW (iBMK W2.B1)CVCL_D3H2 (iBMK W2.Bcl2-14)
CVCL_D3H3 (iBMK W2.Bcl2-15)CVCL_D3H1 (iBMK W2.Bcl2-3)CVCL_D3GX (iBMK W2.D2)
CVCL_D3H4 (iBMK W2.Hras-2)CVCL_D3H5 (iBMK W2.Hras-3)CVCL_D3H6 (iBMK W2.Hras-7)
CVCL_D3H7 (iBMK W2.Raf-13)CVCL_D3H8 (iBMK W2.Raf-15)CVCL_D3H9 (iBMK W2.Raf-16)
CVCL_D3JK (iBMK W2RED)
Sex of cell Sex unspecified
Age at sampling 5D
Category Transformed cell line
Publications

PubMed=11836241; DOI=10.1074/jbc.M109939200
Kurt Degenhardt, Ramya Sundararajan, Tullia Lindsten, Craig B. Thompson, Eileen White;
Bax and Bak independently promote cytochrome C release from mitochondria.
J. Biol. Chem. 277:14127-14134(2002)

PubMed=12242152; DOI=10.1016/S1535-6108(02)00126-5
Kurt Degenhardt, Guang-Hua Chen, Tullia Lindsten, Eileen White;
BAX and BAK mediate p53-independent suppression of tumorigenesis.
Cancer Cell 2:193-203(2002)

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Robin Mathew, Kurt Degenhardt, Liti Haramaty, Cristina M. Karp, Eileen White;
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

Cross-references
Cell line collections (Providers) ABM; T0082
Encyclopedic resources Wikidata; Q127382239
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4