Cellosaurus logo
expasy logo

Cellosaurus A4.6.1 (CVCL_D3F4)

[Text version]
Cell line name A4.6.1
Synonyms A.4.6.1
Accession CVCL_D3F4
Resource Identification Initiative To cite this cell line use: A4.6.1 (RRID:CVCL_D3F4)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized bevacizumab (Avastin) therapeutic antibody used for the treatment of a number of cancers and of age-related macular degeneration.
Monoclonal antibody isotype: IgG1.
Monoclonal antibody target: UniProtKB; P15692; Human VEGFA.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3412 (P3X63Ag8U.1)
Category Hybridoma
Publications

PubMed=1380254; DOI=10.3109/08977199209023937
Kim K.J., Li B., Houck K.A., Winer J., Ferrara N.
The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies.
Growth Factors 7:53-64(1992)

Cross-references
Biological sample resources ABCD; ABCD_AE653
Encyclopedic resources Wikidata; Q127378814
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2