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Cellosaurus Y-MESO-14/hPDPN (CVCL_D2U3)

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Cell line name Y-MESO-14/hPDPN
Accession CVCL_D2U3
Resource Identification Initiative To cite this cell line use: Y-MESO-14/hPDPN (RRID:CVCL_D2U3)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:29602; PDPN.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Sequence variations
  • Gene deletion; HGNC; HGNC:6515; LATS2; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:950; BAP1; Simple; p.Lys116Glyfs*5 (c.349_359del11); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000457921; Zygosity=Unspecified (from parent cell line).
Disease Pleural biphasic mesothelioma (NCIt: C45665)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5179 (Y-MESO-14)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=25080943; DOI=10.1038/srep05924; PMCID=PMC4118152
Yukinari Kato, Mika Kato Kaneko;
A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.
Sci. Rep. 4:5924.1-5924.9(2014)

PubMed=28387591; DOI=10.1089/mab.2017.0001
Shinji Yamada, Satoshi Ogasawara, Mika Kato Kaneko, Yukinari Kato;
LpMab-23: a cancer-specific monoclonal antibody against human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 36:72-76(2017)

Cross-references
Encyclopedic resources Wikidata; Q127384730
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4