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Cellosaurus (CVCL_D2SU)

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Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Phenotyping; shRNA library screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=17363583).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=12068308; PubMed=15048078; PubMed=15467732; PubMed=17363583; PubMed=22383533; Cosmic-CLP=906830; DepMap=ACH-000580).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Ter157Serext*13 (c.470G>C); Zygosity=Homozygous (PubMed=9354451; DepMap=ACH-000580).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American1.03
East Asian, North2.04
East Asian, South0
South Asian0
European, North63.48
European, South33.45
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): AddexBio=C0020002/443; ATCC=CRL-1585; Cosmic-CLP=906830; ECACC=87090201; PubMed=25877200

Markers:

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Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number47