Cellosaurus logo
expasy logo

Cellosaurus LN229/hPD-L1 (CVCL_D2S5)

[Text][XML][JSON]
Cell line name LN229/hPD-L1
Accession CVCL_D2S5
Resource Identification Initiative To cite this cell line use: LN229/hPD-L1 (RRID:CVCL_D2S5)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:17635; CD274 (Note=With a C-terminal DMVNPGLEDRIE = RAP-tag and GDGMVPPGIEDK = MAP-tag).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=29608408; DOI=10.1089/mab.2018.0004
Shinji Yamada, Shunsuke Itai, Takuro Nakamura, Miyuki Yanaka, Yao-Wen Chang, Hiroyoshi Suzuki, Mika Kato Kaneko, Yukinari Kato;
Monoclonal antibody L1Mab-13 detected human PD-L1 in lung cancers.
Monoclon. Antib. Immunodiagn. Immunother. 37:110-115(2018)

Cross-references
Encyclopedic resources Wikidata; Q127382606
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3