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Cellosaurus PANC1/CD44v3-10 (CVCL_D2RB)

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Cell line name PANC1/CD44v3-10
Accession CVCL_D2RB
Resource Identification Initiative To cite this cell line use: PANC1/CD44v3-10 (RRID:CVCL_D2RB)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1681; CD44 (Note=Isoform v3-10; with a N-terminal GLEGGVAMPGAEDDVV = PA16-tag).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=37489367; DOI=10.3390/antib12030045; PMCID=PMC10366929
Hiroyuki Suzuki, Nohara Goto, Tomohiro Tanaka, Tsunenori Ouchida, Mika Kato Kaneko, Yukinari Kato;
Development of a novel anti-CD44 variant 8 monoclonal antibody C44Mab-94 against gastric carcinomas.
Antibodies (Basel) 12:45.1-45.17(2023)

PubMed=37504249; DOI=10.3390/cimb45070333; PMCID=PMC10378409
Kenichiro Ishikawa, Hiroyuki Suzuki, Mika Kato Kaneko, Yukinari Kato;
Establishment of a novel anti-CD44 variant 10 monoclonal antibody C44Mab-18 for immunohistochemical analysis against oral squamous cell carcinomas.
Curr. Issues Mol. Biol. 45:5248-5262(2023)

Cross-references
Encyclopedic resources Wikidata; Q127383007
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3