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Cellosaurus J3T-Bg (CVCL_D2PM)

[Text version]
Cell line name J3T-Bg
Synonyms J3T-BG; J3TBg; J3TBG
Accession CVCL_D2PM
Resource Identification Initiative To cite this cell line use: J3T-Bg (RRID:CVCL_D2PM)
Comments Characteristics: Established from a tumor obtained by subcutaneous implantation of the parent cell line in BiegeNude-xid mice (PubMed=22002975).
Omics: Variations; SNP array analysis.
Miscellaneous: STR profile carried out by CLS and provided by Schrock, Morgan S. The STR profile has 3 additional loci not in standard set: PEZ2:128,140, PEZ15:208 and PEZ17:202,206.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Canine glioma (NCIt: C129297)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Boston Terrier; VBO=VBO_0200204.
Hierarchy Parent: CVCL_W822 (J3T)
Children:
CVCL_D2PQ (J3T-BG/CCNU)CVCL_D2PR (J3T-BG/TMZ)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
Dog FHC2010229,237
Dog FHC2054170,174
Dog FHC2079266,278
Dog PEZ1114,118
Dog PEZ12294
Dog PEZ6188,197
Dog PEZ8231,235

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Publications

PubMed=22002975; DOI=10.1177/0300985811424734
York D., Higgins R.J., LeCouteur R.A., Wolfe A.N., Grahn R.A., Olby N.J., Campbell M., Dickinson P.J.
TP53 mutations in canine brain tumors.
Vet. Pathol. 49:796-801(2012)

PubMed=27251041; DOI=10.1093/jnen/nlw042; PMCID=PMC4913437
Dickinson P.J., York D., Higgins R.J., LeCouteur R.A., Joshi N., Bannasch D.L.
Chromosomal aberrations in canine gliomas define candidate genes and common pathways in dogs and humans.
J. Neuropathol. Exp. Neurol. 75:700-710(2016)

PubMed=28480569; DOI=10.1111/vco.12317; PMCID=PMC5677578
York D., Sproul C.D., Chikere N.L., Dickinson P.J., Angelastro J.M.
Expression and targeting of transcription factor ATF5 in dog gliomas.
Vet. Comp. Oncol. 16:102-107(2018)

PubMed=37254642; DOI=10.1111/vco.12912; PMCID=PMC10524959
Schrock M.S., Zalenski A.A., Tallman M.M., Kollin L., Bratasz A., Weeks G., Miller M.A., Sweeney C.N., Pluhar G.E., Olin M.R., Kisseberth W.C., Bentley R.T., Dickinson P.J., York D., Webb A., Wang X., Moore S., Venere M., Summers M.K.
Establishment and characterization of two novel patient-derived lines from canine high-grade glioma.
Vet. Comp. Oncol. 21:492-502(2023)

PubMed=37365849; DOI=10.1002/vms3.1181; PMCID=PMC10357258
Fuchs D., Rohrer Bley C., Morandi L., Tonon C., Weyland M.S., Nytko-Karouzakis K.J.
Triple combination of lomustine, temozolomide and irradiation reduces canine glioma cell survival in vitro.
Vet. Med. Sci. 9:1573-1583(2023)

Cross-references
Encyclopedic resources Wikidata; Q127382396
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number4