ID   J3T-Bg
AC   CVCL_D2PM
SY   J3T-BG; J3TBg; J3TBG
DR   Wikidata; Q127382396
RX   PubMed=22002975;
RX   PubMed=27251041;
RX   PubMed=28480569;
RX   PubMed=37254642;
RX   PubMed=37365849;
CC   Characteristics: Established from a tumor obtained by subcutaneous implantation of the parent cell line in BiegeNude-xid mice (PubMed=22002975).
CC   Omics: Variations; SNP array analysis.
CC   Miscellaneous: STR profile carried out by CLS and provided by Schrock, Morgan S. The STR profile has 3 additional loci not in standard set: PEZ2:128,140, PEZ15:208 and PEZ17:202,206.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
CC   Breed/subspecies: Boston Terrier; VBO=VBO_0200204.
ST   Source(s): Direct_author_submission
ST   Dog FHC2010: 229,237
ST   Dog FHC2054: 170,174
ST   Dog FHC2079: 266,278
ST   Dog PEZ1: 114,118
ST   Dog PEZ6: 188,197
ST   Dog PEZ8: 231,235
ST   Dog PEZ12: 294
DI   NCIt; C129297; Canine glioma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_W822 ! J3T
SX   Male
AG   10Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 4
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RX   PubMed=22002975; DOI=10.1177/0300985811424734;
RA   York D., Higgins R.J., LeCouteur R.A., Wolfe A.N., Grahn R.A., Olby N.J.,
RA   Campbell M., Dickinson P.J.;
RT   "TP53 mutations in canine brain tumors.";
RL   Vet. Pathol. 49:796-801(2012).
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RX   PubMed=27251041; DOI=10.1093/jnen/nlw042; PMCID=PMC4913437;
RA   Dickinson P.J., York D., Higgins R.J., LeCouteur R.A., Joshi N.,
RA   Bannasch D.L.;
RT   "Chromosomal aberrations in canine gliomas define candidate genes and
RT   common pathways in dogs and humans.";
RL   J. Neuropathol. Exp. Neurol. 75:700-710(2016).
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RX   PubMed=28480569; DOI=10.1111/vco.12317; PMCID=PMC5677578;
RA   York D., Sproul C.D., Chikere N.L., Dickinson P.J., Angelastro J.M.;
RT   "Expression and targeting of transcription factor ATF5 in dog
RT   gliomas.";
RL   Vet. Comp. Oncol. 16:102-107(2018).
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RX   PubMed=37254642; DOI=10.1111/vco.12912; PMCID=PMC10524959;
RA   Schrock M.S., Zalenski A.A., Tallman M.M., Kollin L., Bratasz A.,
RA   Weeks G., Miller M.A., Sweeney C.N., Pluhar G.E., Olin M.R.,
RA   Kisseberth W.C., Bentley R.T., Dickinson P.J., York D., Webb A., Wang X.,
RA   Moore S., Venere M., Summers M.K.;
RT   "Establishment and characterization of two novel patient-derived lines
RT   from canine high-grade glioma.";
RL   Vet. Comp. Oncol. 21:492-502(2023).
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RX   PubMed=37365849; DOI=10.1002/vms3.1181; PMCID=PMC10357258;
RA   Fuchs D., Rohrer Bley C., Morandi L., Tonon C., Weyland M.S.,
RA   Nytko-Karouzakis K.J.;
RT   "Triple combination of lomustine, temozolomide and irradiation reduces
RT   canine glioma cell survival in vitro.";
RL   Vet. Med. Sci. 9:1573-1583(2023).
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