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Cellosaurus STSA-1 (CVCL_D274)

[Text version]
Cell line name STSA-1
Synonyms STSA_1
Accession CVCL_D274
Resource Identification Initiative To cite this cell line use: STSA-1 (RRID:CVCL_D274)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 40 hours (PubMed=27257868).
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; VGNC; 43761; NF1; Simple; p.Met877fs (c.2626dupT); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine soft tissue sarcoma (NCIt: C132276)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Golden Retriever.
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Dog FHC2010235
Dog FHC2054156,164
Dog FHC2079271,275
Dog PEZ1115,119
Dog PEZ12274,285
Dog PEZ20176,184
Dog PEZ3121
Dog PEZ5107,111
Dog PEZ6179
Dog PEZ8228,232

Run an STR similarity search on this cell line

PubMed=22615950; DOI=10.1371/journal.pone.0037239
Gentschev I., Adelfinger M., Josupeit R., Rudolph S., Ehrig K., Donat U., Weibel S., Chen N.G., Yu Y.A., Zhang Q., Heisig M., Thamm D.H., Stritzker J., Macneill A., Szalay A.A.
Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.
PLoS ONE 7:E37239-E37239(2012)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Chemistry resources ChEMBL-Cells; CHEMBL3307911
ChEMBL-Targets; CHEMBL614303
PubChem_Cell_line; CVCL_D274
Encyclopedic resources Wikidata; Q54970642
Gene expression databases GEO; GSM1974799
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number16