ID   STSA-1
AC   CVCL_D274
SY   STSA_1
DR   ChEMBL-Cells; CHEMBL3307911
DR   ChEMBL-Targets; CHEMBL614303
DR   GEO; GSM1974799
DR   PubChem_Cell_line; CVCL_D274
DR   Wikidata; Q54970642
RX   PubMed=22615950;
RX   PubMed=27197945;
RX   PubMed=27257868;
RX   PubMed=31175136;
CC   Part of: FACC canine tumor cell line panel.
CC   Doubling time: 40 hours (PubMed=27257868).
CC   Sequence variation: Mutation; VGNC; 43761; NF1; Simple; p.Met877fs (c.2626dupT); Zygosity=Heterozygous (PubMed=31175136).
CC   Omics: Transcriptome analysis by microarray.
CC   Breed/subspecies: Golden Retriever.
ST   Source(s): PubMed=27197945; PubMed=31175136
ST   Dog FHC2010: 235
ST   Dog FHC2054: 156,164
ST   Dog FHC2079: 271,275
ST   Dog PEZ1: 115,119
ST   Dog PEZ3: 121
ST   Dog PEZ5: 107,111
ST   Dog PEZ6: 179
ST   Dog PEZ8: 228,232
ST   Dog PEZ12: 274,285
ST   Dog PEZ20: 176,184
DI   NCIt; C132276; Canine soft tissue sarcoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Male
AG   7Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 21-03-23; Version: 16
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RX   PubMed=22615950; DOI=10.1371/journal.pone.0037239;
RA   Gentschev I., Adelfinger M., Josupeit R., Rudolph S., Ehrig K.,
RA   Donat U., Weibel S., Chen N.G., Yu Y.A., Zhang Q., Heisig M.,
RA   Thamm D.H., Stritzker J., MacNeill A.L., Szalay A.A.;
RT   "Preclinical evaluation of oncolytic vaccinia virus for therapy of
RT   canine soft tissue sarcoma.";
RL   PLoS ONE 7:E37239-E37239(2012).
//
RX   PubMed=27197945; DOI=10.1111/vco.12192;
RA   Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.;
RT   "The Flint Animal Cancer Center (FACC) canine tumour cell line panel:
RT   a resource for veterinary drug discovery, comparative oncology and
RT   translational medicine.";
RL   Vet. Comp. Oncol. 15:481-492(2017).
//
RX   PubMed=27257868; DOI=10.1371/journal.pone.0156689;
RA   Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.;
RT   "Intrinsic radiosensitivity and cellular characterization of 27 canine
RT   cancer cell lines.";
RL   PLoS ONE 11:E0156689-E0156689(2016).
//
RX   PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346;
RA   Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.;
RT   "Identifying candidate druggable targets in canine cancer cell lines
RT   using whole exome sequencing.";
RL   Mol. Cancer Ther. 18:1460-1471(2019).
//