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Cellosaurus KU-2 (CVCL_D267)

[Text version]
Cell line name KU-2
Synonyms Ku-2; KU2; Keio University-2
Accession CVCL_D267
Resource Identification Initiative To cite this cell line use: KU-2 (RRID:CVCL_D267)
Comments Population: Japanese.
Characteristics: Established from a xenograft maintained in nude mice.
Doubling time: 26 hours (PubMed=661038).
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_W867 (KU2-TP15)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=1263309; DOI=10.1016/S0022-5347(17)59208-3
Katsuoka Y., Baba S., Hata M., Tazaki H.
Transplantation of human renal cell carcinoma to the nude mice: as an intermediate of in vivo and in vitro studies.
J. Urol. 115:373-376(1976)

PubMed=311392; DOI=10.5980/jpnjurol1928.69.12_1623
Jistukawa S.
Normal human lymphocyte mediated cytotoxicity against an established cell line (KU-2) derived from human renal cell carcinoma: role to T & B cells as effector.
Nihon Hinyokika Gakkai Zasshi 69:1623-1638(1978)

PubMed=661038; DOI=10.5980/jpnjurol1928.69.3_285
Katsuoka Y.
Functional and morphological observation of human renal cell carcinoma utilizing nude mouse and cell culture system.
Nihon Hinyokika Gakkai Zasshi 69:285-303(1978)

PubMed=7185005; DOI=10.2302/kjm.31.55
Nagakura K.
Studies on heterogeneity of cultured cell line (KU-2) derived from human renal cell carcinoma: morphology, karyotypes and growth kinetics based on analysis of 13 clones.
Keio J. Med. 31:55-69(1982)

PubMed=3012186; DOI=10.1038/ki.1986.74
Nagakura K., Abe E., Suda T., Hayakawa M., Nakamura H., Tazaki H.
Inhibitory effect of 1 alpha,25-dihydroxyvitamin D3 on the growth of the renal carcinoma cell line.
Kidney Int. 29:834-840(1986)

PubMed=3022569
Katsuoka Y.
Characteristics of an established cell line (KU-2) derived from human renal cell carcinoma: I. Cloning of cells and morphological study of clones; II. Cell kinetics of KU-2 cells; III. Detection of type C virus in the culture.
Hinyokika Kiyo 32:941-948(1986)

PubMed=10496353; DOI=10.1038/sj.bjc.6690688; PMCID=PMC2362876
Sumitomo M., Tachibana M., Murai M., Hayakawa M., Nakamura H., Takayanagi A., Shimizu N.
Overexpression of IL-1ra gene up-regulates interleukin-1beta converting enzyme (ICE) gene expression: possible mechanism underlying IL-1beta-resistance of cancer cells.
Br. J. Cancer 81:277-286(1999)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307795
ChEMBL-Targets; CHEMBL612265
PubChem_Cell_line; CVCL_D267
Encyclopedic resources Wikidata; Q54900673
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number15