Cellosaurus cell line HeLa-MAGI-CCR5 (CVCL

Cellosaurus HeLa-MAGI-CCR5 (CVCL_D260)

Cross-references
Cell line name	HeLa-MAGI-CCR5
Synonyms	HeLa-CD4-CCR5; MAGI-CCR5; MAGI-CCR-5
Accession	CVCL_D260
Resource Identification Initiative	To cite this cell line use: HeLa-MAGI-CCR5 (RRID:CVCL_D260)
Comments	Population: African American. Characteristics: Can be used to can be used to screen for anti-HIV-1 drugs (PubMed=9094670). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1606; CCR5. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_D259 (HeLa-MAGI)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Web pages	Info; IdeaConnection; -; https://www.ideaconnection.com/patents/3382-MAGI-CCR5-Cells.html Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-559.html
Publications	PubMed=9094670; DOI=10.1128/JVI.71.5.3932-3939.1997; PMCID=PMC191545 Bryce Chackerian, E. Michelle Long, Paul A. Luciw, Julie Overbaugh; Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection. J. Virol. 71:3932-3939(1997) PubMed=9201229; DOI=10.1006/viro.1997.8606 Marie A. Vodicka, Wei Chun Goh, Lily I. Wu, Mark E. Rogel, Steven R. Bartz, Vicki L. Schweickart, Carol J. Raport, Michael Emerman; Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses. Virology 233:193-198(1997) PubMed=11158746; DOI=10.1128/AAC.45.2.495-501.2001; PMCID=PMC90318 Atsuko Hachiya, Saori Aizawa-Matsuoka, Mari Tanaka, Yukiko Takahashi, Setsuko Ida, Hiroyuki Gatanaga, Yoshihiro Hirabayashi, Asato Kojima, Masashi Tatsumi, Shinichi Oka; Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5). Antimicrob. Agents Chemother. 45:495-501(2001)
Cell line collections (Providers)	BEI_Resources; ARP-3522
Cell line databases/resources	CLO; CLO_0037219
Anatomy/cell type resources	BTO; BTO_0003587
Encyclopedic resources	Wikidata; Q54882720
Entry history
Entry creation	22-Oct-2012
Last entry update	14-Aug-2025
Version number	26