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Cellosaurus H9-WISP3KO (CVCL_D1GU)

[Text version]
Cell line name H9-WISP3KO
Accession CVCL_D1GU
Resource Identification Initiative To cite this cell line use: H9-WISP3KO (RRID:CVCL_D1GU)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:12771; CCN6.
Omics: Transcriptomics; RNAseq.
Omics: Transcriptomics; RNAseq; Single cell.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Progressive pseudorheumatoid dysplasia (NCIt: C202612)
Progressive pseudorheumatoid arthropathy of childhood (ORDO: Orphanet_1159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=37679035; DOI=10.1136/ard-2023-224304
Chao-Chang Li, Mireia Alemany-Ribes, Rosanne M. Raftery, Uzochi Nwoko, Matthew L. Warman, April M. Craft;
Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for progressive pseudorheumatoid arthropathy of childhood.
Ann. Rheum. Dis. 82:1547-1557(2023)

Cross-references
Encyclopedic resources Wikidata; Q127381017
Gene expression databases GEO; GSM7192008
GEO; GSM7192009
GEO; GSM7192010
GEO; GSM7192028
GEO; GSM7192029
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number4