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Cellosaurus RW-7213 (CVCL_D175)

[Text version]
Cell line name RW-7213
Synonyms RW7213
Accession CVCL_D175
Resource Identification Initiative To cite this cell line use: RW-7213 (RRID:CVCL_D175)
Comments Population: Caucasian.
Microsatellite instability: Stable (MSS) (PubMed=24755471; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Val1320fs*12 (c.3957_3958insT); Zygosity=Unspecified (PubMed=24755471).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=20570890; PubMed=24755471).
Disease Colon mucinous adenocarcinoma (NCIt: C7966)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811
D7S82010
D13S31710,12
D16S5398,10
D21S1130,31
TH016
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=2837323
Tibbetts L.M., Chu M.Y., Vezeridis M.P., Miller P.G., Tibbetts L.L., Poisson M.H., Camara P.D., Calabresi P.
Cell culture of the mucinous variant of human colorectal carcinoma.
Cancer Res. 48:3751-3759(1988)

PubMed=8422623; DOI=10.1002/1097-0142(19930115)71:2<315::AID-CNCR2820710208>3.0.CO;2-B
Tibbetts L.M., Doremus C.M., Tzanakakis G.N., Vezeridis M.P.
Liver metastases with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production.
Cancer 71:315-321(1993)

PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192
Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S., Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C.M., Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M., Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Mouradov D., Sloggett C., Jorissen R.N., Love C.G., Li S., Burgess A.W., Arango D., Strausberg R.L., Buchanan D., Wormald S., O'Connor L., Wilding J.L., Bicknell D.C., Tomlinson I.P.M., Bodmer W.F., Mariadason J.M., Sieber O.M.
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D175
ColonAtlas; RW7213
Encyclopedic resources Wikidata; Q54951485
Gene expression databases GEO; GSM1346886
GEO; GSM1448156
Polymorphism and mutation databases Cosmic; 1479570
Cosmic; 1676734
Cosmic; 2302005
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number20