ID   RW-7213
AC   CVCL_D175
SY   RW7213
DR   cancercelllines; CVCL_D175
DR   ColonAtlas; RW7213
DR   Cosmic; 1479570
DR   Cosmic; 1676734
DR   Cosmic; 2302005
DR   GEO; GSM1346886
DR   GEO; GSM1448156
DR   Wikidata; Q54951485
RX   PubMed=2837323;
RX   PubMed=8422623;
RX   PubMed=20570890;
RX   PubMed=24755471;
RX   PubMed=25926053;
CC   Population: Caucasian.
CC   Microsatellite instability: Stable (MSS) (PubMed=24755471; PubMed=25926053).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Val1320fs*12 (c.3957_3958insT); Zygosity=Unspecified (PubMed=24755471).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=20570890; PubMed=24755471).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
ST   Source(s): PubMed=25926053
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 10,12
ST   D16S539: 8,10
ST   D21S11: 30,31
ST   D5S818: 11
ST   D7S820: 10
ST   TH01: 6
ST   TPOX: 11
ST   vWA: 18
DI   NCIt; C7966; Colon mucinous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   66Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 20
//
RX   PubMed=2837323;
RA   Tibbetts L.M., Chu M.Y., Vezeridis M.P., Miller P.G., Tibbetts L.L.,
RA   Poisson M.H., Camara P.D., Calabresi P.;
RT   "Cell culture of the mucinous variant of human colorectal carcinoma.";
RL   Cancer Res. 48:3751-3759(1988).
//
RX   PubMed=8422623; DOI=10.1002/1097-0142(19930115)71:2<315::AID-CNCR2820710208>3.0.CO;2-B;
RA   Tibbetts L.M., Doremus C.M., Tzanakakis G.N., Vezeridis M.P.;
RT   "Liver metastases with 10 human colon carcinoma cell lines in nude
RT   mice and association with carcinoembryonic antigen production.";
RL   Cancer 71:315-321(1993).
//
RX   PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192;
RA   Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S.,
RA   Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C.M.,
RA   Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M.,
RA   Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.;
RT   "Genomic and biological characterization of exon 4 KRAS mutations in
RT   human cancer.";
RL   Cancer Res. 70:5901-5911(2010).
//
RX   PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013;
RA   Mouradov D., Sloggett C., Jorissen R.N., Love C.G., Li S.,
RA   Burgess A.W., Arango D., Strausberg R.L., Buchanan D., Wormald S.,
RA   O'Connor L., Wilding J.L., Bicknell D.C., Tomlinson I.P.M., Bodmer W.F.,
RA   Mariadason J.M., Sieber O.M.;
RT   "Colorectal cancer cell lines are representative models of the main
RT   molecular subtypes of primary cancer.";
RL   Cancer Res. 74:3238-3247(2014).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G.,
RA   Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S.,
RA   Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M.,
RA   Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.;
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//