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Cellosaurus MLUi007-J (CVCL_D0IJ)

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Cell line name MLUi007-J
Accession CVCL_D0IJ
Resource Identification Initiative To cite this cell line use: MLUi007-J (RRID:CVCL_D0IJ)
Comments From: Medical Faculty, Martin Luther University Halle-Wittenberg; Halle; Germany.
Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=37001364).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D0IA ! MLUi007-A
CVCL_D0IB ! MLUi007-B
CVCL_D0IC ! MLUi007-C
CVCL_D0ID ! MLUi007-D
CVCL_D0IE ! MLUi007-E
CVCL_D0IF ! MLUi007-F
CVCL_D0IG ! MLUi007-G
CVCL_D0IH ! MLUi007-H
CVCL_D0II ! MLUi007-I
Sex of cell Female
Age at sampling 64Y
Category Induced pluripotent stem cell
Publications

PubMed=37001364; DOI=10.1016/j.scr.2023.103072
Matthias Jung, Carla Hartmann, Toni Ehrhardt, Lisa-Maria Peter, Chaudhry Luqman Abid, Bernadette Harwardt, Jana Hirschfeld, Claudia Claus, Undine Haferkamp, Ole Pless, Marina Nastainczyk-Wulf ...Show all 15 authors... , Astrid Kehlen, Dietmar Schlote, Insa S. Schroder, Dan Rujescu; Show fewer authors
Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease.
Stem Cell Res. 69:103072-103072(2023)

PubMed=38612385; DOI=10.3390/ijms25073575; PMCID=PMC11011287
Gabriela Xavier, Alexander Navarrete Santos, Carla Hartmann, Marcos Leite Santoro, Nicole Flegel, Jessica Reinsch, Annika Majer, Toni Ehrhardt, Jenny Pfeifer, Andreas Simm, Thomas Hollemann ...Show all 14 authors... , Sintia Iole Belangero, Dan Rujescu, Matthias Jung; Show fewer authors
Comparison of extracellular vesicles from induced pluripotent stem cell-derived brain cells.
Int. J. Mol. Sci. 25:3575.1-3575.13(2024)

Cross-references
Cell line databases/resources hPSCreg; MLUi007-J
Biological sample resources BioSamples; SAMEA112748717
Encyclopedic resources Wikidata; Q123033072
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3