ID   MLUi007-J
AC   CVCL_D0IJ
DR   BioSamples; SAMEA112748717
DR   hPSCreg; MLUi007-J
DR   Wikidata; Q123033072
RX   PubMed=37001364;
RX   PubMed=38612385;
CC   From: Medical Faculty, Martin Luther University Halle-Wittenberg; Halle; Germany.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=37001364).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C2866; Alzheimer's disease
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_D0IA ! MLUi007-A
OI   CVCL_D0IB ! MLUi007-B
OI   CVCL_D0IC ! MLUi007-C
OI   CVCL_D0ID ! MLUi007-D
OI   CVCL_D0IE ! MLUi007-E
OI   CVCL_D0IF ! MLUi007-F
OI   CVCL_D0IG ! MLUi007-G
OI   CVCL_D0IH ! MLUi007-H
OI   CVCL_D0II ! MLUi007-I
SX   Female
AG   64Y
CA   Induced pluripotent stem cell
DT   Created: 05-10-23; Last updated: 19-12-24; Version: 3
//
RX   PubMed=37001364; DOI=10.1016/j.scr.2023.103072;
RA   Jung, Matthias
RA   Hartmann, Carla
RA   Ehrhardt, Toni
RA   Peter, Lisa-Maria
RA   Abid, Chaudhry Luqman
RA   Harwardt, Bernadette
RA   Hirschfeld, Jana
RA   Claus, Claudia
RA   Haferkamp, Undine
RA   Pless, Ole
RA   Nastainczyk-Wulf, Marina
RA   Kehlen, Astrid
RA   Schlote, Dietmar
RA   Schroder, Insa S.
RA   Rujescu, Dan
RT   "Generation of a set of induced pluripotent stem cell lines from two
RT   Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and
RT   healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study
RT   APOE in aging and disease.";
RL   Stem Cell Res. 69:103072-103072(2023).
//
RX   PubMed=38612385; DOI=10.3390/ijms25073575; PMCID=PMC11011287;
RA   Xavier, Gabriela
RA   Navarrete Santos, Alexander
RA   Hartmann, Carla
RA   Santoro, Marcos Leite
RA   Flegel, Nicole
RA   Reinsch, Jessica
RA   Majer, Annika
RA   Ehrhardt, Toni
RA   Pfeifer, Jenny
RA   Simm, Andreas
RA   Hollemann, Thomas
RA   Belangero, Sintia Iole
RA   Rujescu, Dan
RA   Jung, Matthias
RT   "Comparison of extracellular vesicles from induced pluripotent stem
RT   cell-derived brain cells.";
RL   Int. J. Mol. Sci. 25:3575.1-3575.13(2024).
//