Cellosaurus cell line Huh-7-Lunet/Con1 (CVCL

Cellosaurus Huh-7-Lunet/Con1 (CVCL_CW91)

Cross-references
Cell line name	Huh-7-Lunet/Con1
Synonyms	Huh7 Lunet/Con1; Lunet-Con1
Accession	CVCL_CW91
Resource Identification Initiative	To cite this cell line use: Huh-7-Lunet/Con1 (RRID:CVCL_CW91)
Comments	Population: Japanese. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease	Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_U459 (Huh-7-Lunet)
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Cell line databases/resources	cancercelllines; CVCL_CW91
Anatomy/cell type resources	BTO; BTO_0005726
Encyclopedic resources	Wikidata; Q54896855
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	16