Cellosaurus cell line GSC-0131 (CVCL

Cellosaurus GSC-0131 (CVCL_C9EE)

Cross-references
Cell line name	GSC-0131
Synonyms	GSC0131; 0131
Accession	CVCL_C9EE
Resource Identification Initiative	To cite this cell line use: GSC-0131 (RRID:CVCL_C9EE)
Comments	Group: Cancer stem cell line. Omics: Genomics; Whole exome sequencing. Omics: Phenotyping; CRISPR screening. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val147Asp (c.440T>A); ClinVar=VCV001351017; Zygosity=Homozygous (PubMed=26673326).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Cancer cell line
Publications	PubMed=19427293; DOI=10.1016/j.stem.2009.03.003; PMCID=PMC7227614 Myung Jin Son, Kevin Douglas Woolard, Do-Hyun Nam, Jeongwu Lee, Howard Alan Fine; SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4:440-452(2009) PubMed=26673326; DOI=10.1016/j.celrep.2015.11.021; PMCID=PMC4691575 Chad M. Toledo, Yu Ding, Pia Hoellerbauer, Ryan J. Davis, Ryan Basom, Emily J. Girard, Eunjee Lee, Philip Corrin, Traver Hart, Hamid Bolouri, Jerry Davison ...Show all 27 authors... , Qing Zhang, Justin Hardcastle, Bruce J. Aronow, Christopher L. Plaisier, Nitin S. Baliga, Jason Moffat, Qi Lin, Xiao-Nan Li, Do-Hyun Nam, Jeongwu Lee, Steven M. Pollard, Jun Zhu, Jeffrey J. Delrow, Bruce E. Clurman, James M. Olson, Patrick J. Paddison; Show fewer authors Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells. Cell Rep. 13:2425-2439(2015)
CRISP screens repositories	BioGRID_ORCS_Cell_line; 297
Encyclopedic resources	Wikidata; Q123031372
Gene expression databases	GEO; GSM1715941 GEO; GSM1715942 GEO; GSM1715943 GEO; GSM1715944
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Apr-2025
Version number	4