ID   GSC-0131
AC   CVCL_C9EE
SY   GSC0131; 0131
DR   BioGRID_ORCS_Cell_line; 297
DR   GEO; GSM1715941
DR   GEO; GSM1715942
DR   GEO; GSM1715943
DR   GEO; GSM1715944
DR   Wikidata; Q123031372
RX   PubMed=19427293;
RX   PubMed=26673326;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val147Asp (c.440T>A); ClinVar=VCV001351017; Zygosity=Homozygous (PubMed=26673326).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 4
//
RX   PubMed=19427293; DOI=10.1016/j.stem.2009.03.003; PMCID=PMC7227614;
RA   Son M.J., Woolard K.D., Nam D.-H., Lee J., Fine H.A.;
RT   "SSEA-1 is an enrichment marker for tumor-initiating cells in human
RT   glioblastoma.";
RL   Cell Stem Cell 4:440-452(2009).
//
RX   PubMed=26673326; DOI=10.1016/j.celrep.2015.11.021; PMCID=PMC4691575;
RA   Toledo C.M., Ding Y., Hoellerbauer P., Davis R.J., Basom R.,
RA   Girard E.J., Lee E., Corrin P., Hart T., Bolouri H., Davison J.,
RA   Zhang Q., Hardcastle J., Aronow B.J., Plaisier C.L., Baliga N.S.,
RA   Moffat J., Lin Q., Li X.-N., Nam D.-H., Lee J., Pollard S.M., Zhu J.,
RA   Delrow J.J., Clurman B.E., Olson J.M., Paddison P.J.;
RT   "Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between
RT   PKMYT1 and WEE1 in glioblastoma stem-like cells.";
RL   Cell Rep. 13:2425-2439(2015).
//