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Cellosaurus HeLa RelA-mNeonGreen (CVCL_C9AQ)

[Text version]
Cell line name HeLa RelA-mNeonGreen
Synonyms HeLa p65-mNeonGreen; HeLa RelA
Accession CVCL_C9AQ
Resource Identification Initiative To cite this cell line use: HeLa RelA-mNeonGreen (RRID:CVCL_C9AQ)
Comments Population: African American.
Characteristics: Expression of Cas9 can be induced by doxocycline (from parent cell line).
Characteristics: Transduced with a pR14_p65-mNeonGreen construct (PubMed=31626775).
Transfected with: HGNC; 9955; RELA.
Transfected with: UniProtKB; A0A1S4NYF2; mNeonGreen (derivative of Branchiostoma lanceolatum blFP-Y3).
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: CRISPR phenotypic screen.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C9AP (HeLa-TetR-Cas9)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=31626775; DOI=10.1016/j.cell.2019.09.016
Feldman D., Singh A., Schmid-Burgk J.L., Carlson R.J., Mezger A., Garrity A.J., Zhang F., Blainey P.C.
Optical pooled screens in human cells.
Cell 179:787-799.e17(2019)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1605
Encyclopedic resources Wikidata; Q123031618
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2