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Cellosaurus G523NS-Cas9 (CVCL_C9AB)

[Text version]
Cell line name G523NS-Cas9
Accession CVCL_C9AB
Resource Identification Initiative To cite this cell line use: G523NS-Cas9 (RRID:CVCL_C9AB)
Comments Group: Cancer stem cell line.
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
Omics: CRISPR phenotypic screen.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B4P6 (G523)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line

PubMed=30995489; DOI=10.1016/j.celrep.2019.03.047
MacLeod G., Bozek D.A., Rajakulendran N., Monteiro V., Ahmadi M., Steinhart Z., Kushida M.M., Yu H., Coutinho F.J., Cavalli F.M.G., Restall I.J., Hao X.-G., Hart T., Luchman H.A., Weiss S., Dirks P.B., Angers S.
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells.
Cell Rep. 27:971-986.e9(2019)

CRISP screens repositories BioGRID_ORCS_Cell_line; 1067
Encyclopedic resources Wikidata; Q123031337
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2