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Cellosaurus H1-HeLa+CDHR3 SETD3KO (CVCL_C8ZI)

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Cell line name H1-HeLa+CDHR3 SETD3KO
Accession CVCL_C8ZI
Resource Identification Initiative To cite this cell line use: H1-HeLa+CDHR3 SETD3KO (RRID:CVCL_C8ZI)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:20493; SETD3.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:26308; CDHR3 (Note=With p.Cys529Tyr).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8ZH (H1-HeLa+CHDR3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=31527793; DOI=10.1038/s41564-019-0551-1; PMCID=PMC6879830
Jonathan Diep, Yaw Shin Ooi, Alex W. Wilkinson, Christine E. Peters, Eileen Marie Foy, Jeffrey R. Johnson, James Zengel, Si-Yuan Ding, Kuo-Feng Weng, Orly Laufman, Gwendolyn Jang, Jie-Wei Xu, Tracy Young ...Show all 24 authors... , Erik Verschueren, Kristi J. Kobluk, Joshua E. Elias, Peter Sarnow, Harry B. Greenberg, Ruth Huttenhain, Claude M. Nagamine, Raul Andino-Pavlovsky, Nevan J. Krogan, Or Pinchas Gozani, Jan E. Carette; Show fewer authors
Enterovirus pathogenesis requires the host methyltransferase SETD3.
Nat. Microbiol. 4:2523-2537(2019)

Cross-references
Encyclopedic resources Wikidata; Q123031386
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6