ID   H1-HeLa+CDHR3 SETD3KO
AC   CVCL_C8ZI
DR   Wikidata; Q123031386
RX   PubMed=31527793;
CC   Population: African American.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:20493; SETD3.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:26308; CDHR3 (Note=With p.Cys529Tyr).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C8ZH ! H1-HeLa+CHDR3
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 5
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RX   PubMed=31527793; DOI=10.1038/s41564-019-0551-1; PMCID=PMC6879830;
RA   Diep J., Ooi Y.S., Wilkinson A.W., Peters C.E., Foy E.M., Johnson J.R.,
RA   Zengel J., Ding S.-Y., Weng K.-F., Laufman O., Jang G., Xu J.-W.,
RA   Young T., Verschueren E., Kobluk K.J., Elias J.E., Sarnow P.,
RA   Greenberg H.B., Huttenhain R., Nagamine C.M., Andino-Pavlovsky R.,
RA   Krogan N.J., Gozani O.P., Carette J.E.;
RT   "Enterovirus pathogenesis requires the host methyltransferase SETD3.";
RL   Nat. Microbiol. 4:2523-2537(2019).
//