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Cellosaurus IMC9 (CVCL_C8ZG)

[Text version]
Cell line name IMC9
Accession CVCL_C8ZG
Resource Identification Initiative To cite this cell line use: IMC9 (RRID:CVCL_C8ZG)
Comments Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transformant: Myc.
Omics: Phenotyping; CRISPR screening.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Trp53-/- transgenic.
Age at sampling 12-15FD
Category Cancer cell line
Publications

PubMed=30797773; DOI=10.1016/j.cels.2019.01.004; PMCID=PMC6592847
Codina A., Renauer P.A., Wang G.-C., Chow R.D., Park J.J., Ye H.-H., Zhang K., Dong M.B., Gassaway B., Ye L.-P., Errami Y., Shen L., Chang A., Jain D., Herbst R.S., Bosenberg M.W., Rinehart J., Fan R., Chen S.
Convergent identification and interrogation of tumor-intrinsic factors that modulate cancer immunity in vivo.
Cell Syst. 8:136-151.e7(2019)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 819
Encyclopedic resources Wikidata; Q123032698
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number5