ID   IMC9
AC   CVCL_C8ZG
DR   BioGRID_ORCS_Cell_line; 819
DR   Wikidata; Q123032698
RX   PubMed=30797773;
CC   Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Transformant: Myc.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
CC   Breed/subspecies: C57BL/6 Trp53-/- transgenic.
DI   NCIt; C38756; Hepatocellular carcinoma of the mouse
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
AG   12-15FD
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 5
//
RX   PubMed=30797773; DOI=10.1016/j.cels.2019.01.004; PMCID=PMC6592847;
RA   Codina A., Renauer P.A., Wang G.-C., Chow R.D., Park J.J., Ye H.-H.,
RA   Zhang K., Dong M.B., Gassaway B., Ye L.-P., Errami Y., Shen L.,
RA   Chang A., Jain D., Herbst R.S., Bosenberg M.W., Rinehart J., Fan R.,
RA   Chen S.;
RT   "Convergent identification and interrogation of tumor-intrinsic
RT   factors that modulate cancer immunity in vivo.";
RL   Cell Syst. 8:136-151.e7(2019).
//