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Cellosaurus LE/6 (CVCL_C8XH)

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Cell line name LE/6
Accession CVCL_C8XH
Resource Identification Initiative To cite this cell line use: LE/6 (RRID:CVCL_C8XH)
Comments Doubling time: 24 hours (Note=At <=20 passages), 16 hours (Note=At >=50 passages) (PubMed=2440558).
Transformant: ChEBI; CHEBI_68664; DL-ethionine.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic oval stem cell; CL=CL_0002196.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Holtzman Sprague Dawley (HotHsd:SD); RS=RS_0002942.
Sex of cell Male
Age at sampling 12-14W
Category Transformed cell line
Publications

PubMed=2440558
Lundy Braun, Michele Goyette, Paul Yaswen, Nancy L. Thompson, Nelson Fausto;
Growth in culture and tumorigenicity after transfection with the ras oncogene of liver epithelial cells from carcinogen-treated rats.
Cancer Res. 47:4116-4124(1987)

PubMed=2647288
Lundy Braun, Ryoko Mikumo, Nelson Fausto;
Production of hepatocellular carcinoma by oval cells: cell cycle expression of c-myc and p53 at different stages of oval cell transformation.
Cancer Res. 49:1554-1561(1989)

Cross-references
Encyclopedic resources Wikidata; Q123032945
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number5