ID LE/6 AC CVCL_C8XH DR Wikidata; Q123032945 RX PubMed=2440558; RX PubMed=2647288; CC Doubling time: 24 hours (Note=At <=20 passages), 16 hours (Note=At >=50 passages) (PubMed=2440558). CC Transformant: ChEBI; CHEBI_68664; DL-ethionine. CC Derived from site: In situ; Liver; UBERON=UBERON_0002107. CC Cell type: Hepatic oval stem cell; CL=CL_0002196. CC Breed/subspecies: Holtzman Sprague Dawley (HotHsd:SD); RS=RS_0002942. OX NCBI_TaxID=10116; ! Rattus norvegicus (Rat) SX Male AG 12-14W CA Transformed cell line DT Created: 05-10-23; Last updated: 10-04-25; Version: 5 // RX PubMed=2440558; RA Braun L., Goyette M., Yaswen P., Thompson N.L., Fausto N.; RT "Growth in culture and tumorigenicity after transfection with the ras RT oncogene of liver epithelial cells from carcinogen-treated rats."; RL Cancer Res. 47:4116-4124(1987). // RX PubMed=2647288; RA Braun L., Mikumo R., Fausto N.; RT "Production of hepatocellular carcinoma by oval cells: cell cycle RT expression of c-myc and p53 at different stages of oval cell RT transformation."; RL Cancer Res. 49:1554-1561(1989). //