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Cellosaurus M2-CD83 (CVCL_C8SK)

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Cell line name M2-CD83
Accession CVCL_C8SK
Resource Identification Initiative To cite this cell line use: M2-CD83 (RRID:CVCL_C8SK)
Comments Genetic integration: Method=Transduction; Gene=MGI; MGI:1328316; Cd83.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCIt; C17231; Ultraviolet radiation.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_F684 (K1735-M2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=15051893; DOI=10.1073/pnas.0400880101; PMCID=PMC387361
Shi-Lin Yang, Yi Yang, John Raycraft, Hong-Tao Zhang, Sandra Kanan, Ya-Jun Guo, Ze'ev A. Ronai, Ingegerd Hellstrom, Karl Erik Hellstrom;
Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137.
Proc. Natl. Acad. Sci. U.S.A. 101:4990-4995(2004)

Cross-references
Encyclopedic resources Wikidata; Q123032991
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number5