Cellosaurus logo
expasy logo

Cellosaurus MOPC-315.BM.Luc+ (CVCL_C8RN)

[Text][XML][JSON]
Cell line name MOPC-315.BM.Luc+
Synonyms MOPC-315.BM luciferase+; MOPC315.BM.Luc
Accession CVCL_C8RN
Resource Identification Initiative To cite this cell line use: MOPC-315.BM.Luc+ (RRID:CVCL_C8RN)
Comments Characteristics: Homes to and expands in the bone marrow after intra-venous injection (PubMed=23284805).
Monoclonal antibody isotype: IgA, lambda.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Transformant: DrugBank; DB11057; Mineral oil.
Derived from site: In situ; Hypodermis; UBERON=UBERON_0002072.
Cell type: B-cell; CL=CL_0000236.
Disease Mouse plasmacytoma (NCIt: C21631)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_VI68 (MOPC-315.BM)
Category Cancer cell line
Web pages Provider; I2B; P-77; http://inven2biologics.com/shop/cell-lines/human/mopc315bm-luciferase-multiple-myeloma
Publications

PubMed=23284805; DOI=10.1371/journal.pone.0051892; PMCID=PMC3527494
Peter Olaf Hofgaard, Henriette C. Jodal, Kurt Bommert, Bertrand Huard, Jo Caers, Harald Carlsen, Rolf Schwarzer, Nicole Schunemann, Franziska Jundt, Mona Mari Lindeberg, Bjarne Bogen;
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
PLoS ONE 7:e51892.1-e51892.13(2012)

PubMed=23300660; DOI=10.1371/journal.pone.0052398; PMCID=PMC3530556
Simone S. Riedel, Anja Mottok, Christian Brede, Carina A. Bauerlein, Ana-Laura Jordan Garrote, Miriam Ritz, Katharina Mattenheimer, Andreas Rosenwald, Hermann Einsele, Bjarne Bogen, Andreas Beilhack;
Non-invasive imaging provides spatiotemporal information on disease progression and response to therapy in a murine model of multiple myeloma.
PLoS ONE 7:e52398.1-e52398.13(2012)

Cross-references
Encyclopedic resources Wikidata; Q123033115
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number5