ID   MOPC-315.BM.Luc+
AC   CVCL_C8RN
SY   MOPC-315.BM luciferase+; MOPC315.BM.Luc
DR   Wikidata; Q123033115
RX   PubMed=23284805;
RX   PubMed=23300660;
WW   Provider; I2B; P-77; http://inven2biologics.com/shop/cell-lines/human/mopc315bm-luciferase-multiple-myeloma
CC   Characteristics: Homes to and expands in the bone marrow after intra-venous injection (PubMed=23284805).
CC   Monoclonal antibody isotype: IgA, lambda.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: DrugBank; DB11057; Mineral oil.
CC   Derived from site: In situ; Hypodermis; UBERON=UBERON_0002072.
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: BALB/c.
DI   NCIt; C21631; Mouse plasmacytoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_VI68 ! MOPC-315.BM
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 4
//
RX   PubMed=23284805; DOI=10.1371/journal.pone.0051892; PMCID=PMC3527494;
RA   Hofgaard P.O., Jodal H.C., Bommert K., Huard B., Caers J., Carlsen H.,
RA   Schwarzer R., Schunemann N., Jundt F., Lindeberg M.M., Bogen B.;
RT   "A novel mouse model for multiple myeloma (MOPC315.BM) that allows
RT   noninvasive spatiotemporal detection of osteolytic disease.";
RL   PLoS ONE 7:e51892.1-e51892.13(2012).
//
RX   PubMed=23300660; DOI=10.1371/journal.pone.0052398; PMCID=PMC3530556;
RA   Riedel S.S., Mottok A., Brede C., Bauerlein C.A., Jordan Garrote A.-L.,
RA   Ritz M., Mattenheimer K., Rosenwald A., Einsele H., Bogen B.,
RA   Beilhack A.;
RT   "Non-invasive imaging provides spatiotemporal information on disease
RT   progression and response to therapy in a murine model of multiple
RT   myeloma.";
RL   PLoS ONE 7:e52398.1-e52398.13(2012).
//