Cellosaurus cell line (CVCL

Cellosaurus (CVCL_C8RK)

Cross-references
Comments	Problematic cell line: Contaminated. Shown to be a Lu-134-A (or Lu-134-B) derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a 61 year old male patient with small cell lung carcinoma. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00232. Population: Japanese. Omics: Transcriptomics; Microarray. Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Leu (c.833C>T); ClinVar=VCV000232497; Zygosity=Unspecified (PubMed=1312700; PubMed=10536175).
Disease	Lung small cell carcinoma (NCIt: C4917) Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin	Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1387 (Lu-134-A)
Sex of cell	Male
Age at sampling	80Y
Category	Cancer cell line
Web pages	Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx Info; RCB; -; https://cell.brc.riken.jp/ja/quality/str/origin/confirm_report/confirm_table4
Publications	Kurt Neumann, Miguel Beato; Establishment of rat endometrial cell lines by retroviral mediated transfer of immortalizing and transforming oncogenes. Oncogene 5:787-794(1990) William L. Perry 3rd; Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS, and MXI1 in human glioblastoma multiforme. Int. J. Oncol. 12:905-910(1998) Bo Ahren, Goran Stenman, Ola Nilsson; A transplantable human carcinoid as model for somatostatin receptor-mediated and amine transporter-mediated radionuclide uptake. Am. J. Pathol. 158:745-755(2001) Jpn. J. Cancer Res. 93:667-676(2002) Hiroyuki Kato, Eizo Kimura, Makoto Yasuda, Tadao Tanaka, Hiroshi Ishikawa; Establishment and characterization of JHUCS-1 cell line derived from carcinosarcoma of the human uterus. Hum. Cell 17:139-144(2004) Int. J. Cancer 122:2719-2725(2008) Christopher M. Heaphy, Nicholas J. Roberts, Laura DeLong Wood; Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas. Lab. Invest. 100:1003-1013(2020)
Cell line collections (Providers)	RCB; RCB0465 - Discontinued
Encyclopedic resources	Wikidata; Q54903190
Gene expression databases	GEO; GSM17309
Polymorphism and mutation databases	Cosmic; 844807 Cosmic; 918004 Cosmic; 1212192 Cosmic; 1571748 Cosmic; 2668337 IARC_TP53; 1013
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	28