Cellosaurus cell line WA01 TH-TdTomato (CVCL

Cross-references
Cell line name	WA01 TH-TdTomato
Synonyms	TH-TdTomato WA01 Reporter line; WA01-TH-WT
Accession	CVCL_C8FP
Resource Identification Initiative	To cite this cell line use: WA01 TH-TdTomato (RRID:CVCL_C8FP)
Comments	Characteristics: Fluorescent (tdTomato) reporter cell line for TH expression. Using CRISPR/Cas9 a P2A-tdTomato construct was introduced in the C-terminal end of TH (PubMed=31902706). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)). Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9771 (WA01)
Sex of cell	Male
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=31902706; DOI=10.1016/j.stemcr.2019.12.005; PMCID=PMC6962705 Tim Ahfeldt, Alban Ordureau, Christina Bell, Lily Sarrafha, Chi-Cheng Sun, Silvia Piccinotti, Tobias Grass, Gustavo Morrone Parfitt, Joao A. Paulo, Fumiki Yanagawa, Takayuki Uozumi ...Show all 14 authors... , Yasujiro Kiyota, Jeffrey Wade Harper, Lee L. Rubin; Show fewer authors Pathogenic pathways in early-onset autosomal recessive Parkinson's disease discovered using isogenic human dopaminergic neurons. Stem Cell Reports 14:75-90(2020)
Encyclopedic resources	Wikidata; Q123033791
Entry history
Entry creation	29-Jun-2023
Last entry update	10-Sep-2024
Version number	3