ID   WA01 TH-TdTomato
AC   CVCL_C8FP
SY   TH-TdTomato WA01 Reporter line; WA01-TH-WT
DR   Wikidata; Q123033791
RX   PubMed=31902706;
CC   Characteristics: Fluorescent (tdTomato) reporter cell line for TH expression. Using CRISPR/Cas9 a P2A-tdTomato construct was introduced in the C-terminal end of TH (PubMed=31902706).
CC   Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9771 ! WA01
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 29-06-23; Last updated: 10-09-24; Version: 3
//
RX   PubMed=31902706; DOI=10.1016/j.stemcr.2019.12.005; PMCID=PMC6962705;
RA   Ahfeldt T., Ordureau A., Bell C., Sarrafha L., Sun C.-C., Piccinotti S.,
RA   Grass T., Parfitt G.M., Paulo J.A., Yanagawa F., Uozumi T., Kiyota Y.,
RA   Harper J.W., Rubin L.L.;
RT   "Pathogenic pathways in early-onset autosomal recessive Parkinson's
RT   disease discovered using isogenic human dopaminergic neurons.";
RL   Stem Cell Reports 14:75-90(2020).
//