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Cellosaurus TK 173 (CVCL_C8FA)

[Text version]
Cell line name TK 173
Synonyms Tk 173; TK-173; tNKF; transformed Normal Kidney Fibroblasts
Accession CVCL_C8FA
Resource Identification Initiative To cite this cell line use: TK 173 (RRID:CVCL_C8FA)
Comments Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-gpt).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Renal interstitial fibroblast; CL=CL_1000692.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7773632
Muller G.A., Frank J., Rodemann H.P., Engler-Blum G.
Human renal fibroblast cell lines (tFKIF and tNKF) are new tools to investigate pathophysiologic mechanisms of renal interstitial fibrosis.
Exp. Nephrol. 3:127-133(1995)

PubMed=11702000; DOI=10.1159/000052639
Grunewald R.W., Ehrhard M., Fiedler G.M., Schuttert J.B., Oppermann M., Muller G.A.
Evidence for a sorbitol transport system in immortalized human renal interstitial cells.
Exp. Nephrol. 9:405-411(2001)

PubMed=12684791; DOI=10.1007/s00424-003-1026-y
Schuttert J.B., Liu M.H., Gliem N., Fiedler G.M., Zopf S., Mayer C., Muller G.A., Grunewald R.W.
Human renal fibroblasts derived from normal and fibrotic kidneys show differences in increase of extracellular matrix synthesis and cell proliferation upon angiotensin II exposure.
Pflugers Arch. 446:387-393(2003)

Cross-references
Encyclopedic resources Wikidata; Q123033618
Entry history
Entry creation29-Jun-2023
Last entry update10-Apr-2025
Version number5