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Cellosaurus RPE1-SS48 (CVCL_C8DQ)

[Text version]
Cell line name RPE1-SS48
Synonyms RPE1SS48
Accession CVCL_C8DQ
Resource Identification Initiative To cite this cell line use: RPE1-SS48 (RRID:CVCL_C8DQ)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Characteristics: Control cell line for a set aneuploid derivatives (PubMed=33505028).
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4388 (hTERT-RPE1)
Sex of cell Female
Age at sampling 1Y
Category Telomerase immortalized cell line

PubMed=33505028; DOI=10.1038/s41586-020-03114-6
Cohen-Sharir Y., McFarland J.M., Abdusamad M., Marquis C., Bernhard S.V., Kazachkova M., Tang H., Ippolito M.R., Laue K., Zerbib J., Malaby H.L.H., Jones A., Stautmeister L.M., Bockaj I., Wardenaar R., Lyons N., Nagaraja A.K., Bass A.J., Spierings D.C.J., Foijer F., Beroukhim R., Santaguida S., Golub T.R., Stumpff J., Storchova Z., Ben-David U.
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.
Nature 590:486-491(2021)

Cell line databases/resources DepMap; ACH-002462
Entry history
Entry creation29-Jun-2023
Last entry update05-Oct-2023
Version number2