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Cellosaurus SW480 M13OE (CVCL_C8D6)

[Text version]
Cell line name SW480 M13OE
Synonyms SW480 MUC13 OverExpressing
Accession CVCL_C8D6
Resource Identification Initiative To cite this cell line use: SW480 M13OE (RRID:CVCL_C8D6)
Comments Population: Caucasian.
Characteristics: Transfected with GFP-tagged MUC13 (PubMed=24097071).
Doubling time: 29.4 hours (PubMed=24097071).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7511; MUC13.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=24097071; DOI=10.1007/s00535-013-0885-z; PMCID=PMC3979492
Brij K. Gupta, Diane M. Maher, Mara C. Ebeling, Phillip D. Stephenson, Susan E. Puumala, Michael R. Koch, Hiroyuki Aburatani, Meena Jaggi, Subhash C. Chauhan;
Functions and regulation of MUC13 mucin in colon cancer cells.
J. Gastroenterol. 49:1378-1391(2014)

Cross-references
Encyclopedic resources Wikidata; Q123033580
Entry history
Entry creation29-Jun-2023
Last entry update14-Aug-2025
Version number6