ID   SW480 M13OE
AC   CVCL_C8D6
SY   SW480 MUC13 OverExpressing
DR   Wikidata; Q123033580
RX   PubMed=24097071;
CC   Population: Caucasian.
CC   Characteristics: Transfected with GFP-tagged MUC13 (PubMed=24097071).
CC   Doubling time: 29.4 hours (PubMed=24097071).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 7511; MUC13.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0546 ! SW480
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 29-06-23; Last updated: 30-01-24; Version: 2
//
RX   PubMed=24097071; DOI=10.1007/s00535-013-0885-z;
RA   Gupta B.K., Maher D.M., Ebeling M.C., Stephenson P.D., Puumala S.E.,
RA   Koch M.R., Aburatani H., Jaggi M., Chauhan S.C.;
RT   "Functions and regulation of MUC13 mucin in colon cancer cells.";
RL   J. Gastroenterol. 49:1378-1391(2014).
//