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Cellosaurus HC1047 (CVCL_C8C4)

[Text version]
Cell line name HC1047
Synonyms HC47
Accession CVCL_C8C4
Resource Identification Initiative To cite this cell line use: HC1047 (RRID:CVCL_C8C4)
Comments Characteristics: Overproduces adenylate deaminase (PubMed=3785179; PubMed=7162515).
Selected for resistance to: ChEBI; CHEBI_16213; Coformycin.
Selected for resistance to: ChEBI; CHEBI_28680; Cytarabine (Arabinosylcytosine; Ara-C).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_C8BY (HC4)
Children:
CVCL_C8C7 (HC50474)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7162515; DOI=10.1128/mcb.2.11.1346-1353.1982; PMCID=PMC369939
Debatisse M., Berry M., Buttin G.
Stepwise isolation and properties of unstable Chinese hamster cell variants that overproduce adenylate deaminase.
Mol. Cell. Biol. 2:1346-1353(1982)

PubMed=3785179; DOI=10.1128/mcb.6.5.1776-1781.1986; PMCID=PMC367706
Debatisse M., Hyrien O., Petit-Koskas E., Robert de Saint-Vincent B., Buttin G.
Segregation and rearrangement of coamplified genes in different lineages of mutant cells that overproduce adenylate deaminase.
Mol. Cell. Biol. 6:1776-1781(1986)

PubMed=8569793; DOI=10.1016/0027-5107(95)00153-0
Lunel-Orsini C., Buttin G., Robert de Saint-Vincent B.
Reversion in Chinese hamster lines amplified at the AMPD2 locus: spontaneous and benzamide-stimulated gradual loss of amplified alleles of marker genes.
Mutat. Res. 349:63-75(1996)

Cross-references
Encyclopedic resources Wikidata; Q123031505
Entry history
Entry creation29-Jun-2023
Last entry update19-Dec-2024
Version number3