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Cellosaurus MM418 (CVCL_C843)

[Text version]
Cell line name MM418
Synonyms MM 418; 418
Accession CVCL_C843
Resource Identification Initiative To cite this cell line use: MM418 (RRID:CVCL_C843)
Comments Characteristics: Highly pigmented.
Doubling time: 35.8 hours (PubMed=2798324).
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Back, skin; UBERON=UBERON_0001068.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_UM71 (MM418-1)CVCL_UM72 (MM418-5)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=4059365; DOI=10.1111/j.1751-1097.1985.tb08944.x
Peter G. Parsons, Ian P. Hayward;
Inhibition of DNA repair synthesis by sunlight.
Photochem. Photobiol. 42:287-293(1985)

PubMed=3756862
Kevin Maynard, Peter G. Parsons;
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

PubMed=3127479; DOI=10.1111/1523-1747.ep12461022
Max McEwan, Peter G. Parsons, Denis J. Moss;
Monoclonal antibody against human tyrosinase and reactive with melanotic and amelanotic melanoma cells.
J. Invest. Dermatol. 90:515-519(1988)

PubMed=2798324; DOI=10.1111/j.1600-0749.1989.tb00211.x
J. Keith Brown, Max H. Mountford, Barry J. Allen, Yutaka Mishima, Masamitsu Ichihashi, Peter G. Parsons;
Neutron irradiation of human melanoma cells.
Pigment Cell Res. 2:319-324(1989)

PubMed=2798328; DOI=10.1111/j.1600-0749.1989.tb00217.x
David H. Barkla, Barry J. Allen, J. Keith Brown, Max H. Mountford, Yutaka Mishima, Masamitsu Ichihashi;
Morphological changes in human melanoma cells following irradiation with thermal neutrons.
Pigment Cell Res. 2:345-348(1989)

PubMed=1697409
Georgia Chenevix-Trench, Nicholas Gordon Martin, Kay Adrian Oswald Ellem;
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Oncogene 5:1187-1193(1990)

PubMed=7520026; DOI=10.1002/ijc.2910580413
Peter Hersey, Zhao-Yi Si, Melanie J. Smith, Wayne D. Thomas;
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=9354451
Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward;
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Mitchell S. Stark, Nicholas K. Hayward;
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C843
Chemistry resources ChEMBL-Cells; CHEMBL3307300
ChEMBL-Targets; CHEMBL614131
PubChem_Cell_line; CVCL_C843
Encyclopedic resources Wikidata; Q54906127
Gene expression databases GEO; GSM226682
Polymorphism and mutation databases Cosmic; 928707
Progenetix; CVCL_C843
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number22