Cellosaurus cell line WIBRe001-A-25 (CVCL

Cellosaurus WIBRe001-A-25 (CVCL_C7VJ)

Cross-references
Cell line name	WIBRe001-A-25
Synonyms	WIBR3_LRRK2_G2019S_65_Homo; AECMe002-A-25
Accession	CVCL_C7VJ
Resource Identification Initiative	To cite this cell line use: WIBRe001-A-25 (RRID:CVCL_C7VJ)
Comments	From: Albert Einstein College of Medicine; New York; USA. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations	Mutation; HGNC; 18618; LRRK2; Simple_edited; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Homozygous; Note=By prime editing (DOI=10.1101/2024.02.12.579917).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9767 (WIBR3)
Sex of cell	Female
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	DOI=10.1101/2024.02.12.579917 Busquets Figueras O., Li H.-Q., Syed K.M., Alvarez Jerez P., Dunnack J., Lo Bu R., Verma Y., Pangilinan G.R., Martin A., Straub J., Du Y.-X., Simon V.M., Poser S., Bush Z., Diaz J., Sahagun A., Gao J.-P., Hernandez D.G., Levine K.S., Booth E.O., Bateup H.S., Rio D.C., Hockemeyer D., Blauwendraat C., Soldner F.F. iSCORE-PD: an isogenic stem cell collection to research Parkinson disease. bioRxiv 2024:02.12.579917-02.12.579917(2024)
Cell line databases/resources	hPSCreg; WIBRe001-A-25
Biological sample resources	BioSamples; SAMEA114404499
Encyclopedic resources	Wikidata; Q123033893
Entry history
Entry creation	29-Jun-2023
Last entry update	02-May-2024
Version number	4